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Lexus IS300 (XE10 / JCE10) 2001-05 2JZ-GE VVT-i → Motorsport Electronics ME221 (auto)

Lexus IS300 (XE10 / JCE10) 2001-05 2JZ-GE VVT-i — Motorsport Electronics — ME221
⚠ NOT CHECKED. Don't build from this.
Drawn by Michael Gnankou · Rev 0 · draft · 2026-10-11

Before you start

Not confident with automotive wiring? Have a professional harness builder or tuner do it, or check your work before first power-up. A wiring mistake can damage the ECU, the engine or the car, or start a fire.

Statusdraft · not yet verified: nobody has reported building and running this harness
Open errors5: read the Findings page before cutting any wire
Size of the job49 wires · 10 connectors · 0 part lines
ToolsCrimp and extraction tools for each terminal family (see Connectors) · wire strippers · multimeter · heat gun + heat-shrink
Order of work1. Check every part against the parts list. 2. Cut and label every wire (labels: Export → Wire labels). 3. Crimp and pin connector by connector, ticking the build checklist. 4. Run the bench test with nothing plugged in and the battery disconnected. 5. Only then connect the ECU and power up.

Build checklist

Tick each box as you go. Continuity: meter from end to end, expect under 1 Ω.

WireFromToGaugeColourCutLabelCrimp ACrimp BPin APin BContinuity
W1OEM-E2-13SP-14V-10.85☐☐☐☐☐☐☐
W2OEM-E3-16SP-14V-10.85☐☐☐☐☐☐☐
W3OEM-E3-7SP-14V-10.85☐☐☐☐☐☐☐
W4OEM-E3-8SP-14V-10.85☐☐☐☐☐☐☐
W5SP-14V-1ME221-C1-150.85☐☐☐☐☐☐☐
W6SP-14V-1ME221-C1-640.85☐☐☐☐☐☐☐
W7OEM-E6-17SP-GND-10.85☐☐☐☐☐☐☐
W8OEM-E7-21SP-GND-10.85☐☐☐☐☐☐☐
W9SP-GND-1ME221-C1-100.85☐☐☐☐☐☐☐
W10SP-GND-1ME221-C1-610.85☐☐☐☐☐☐☐
W11SP-GND-1ME221-C1-890.85☐☐☐☐☐☐☐
W12SP-GND-1ME221-C1-900.85☐☐☐☐☐☐☐
W13OEM-E6-18SP-0V-10.5☐☐☐☐☐☐☐
W14OEM-E6-19SP-0V-10.5☐☐☐☐☐☐☐
W15OEM-E7-22SP-0V-10.5☐☐☐☐☐☐☐
W16SP-0V-1ME221-C1-520.5☐☐☐☐☐☐☐
W17SP-0V-1ME221-C1-840.5☐☐☐☐☐☐☐
W18OEM-E6-2ME221-C1-450.5☐☐☐☐☐☐☐
W19OEM-E7-23ME221-C1-800.5☐☐☐☐☐☐☐
W20OEM-E7-10ME221-C1-220.5☐☐☐☐☐☐☐
W21OEM-E7-28ME221-C1-530.5☐☐☐☐☐☐☐
W22OEM-E7-11ME221-C1-320.5☐☐☐☐☐☐☐
W23OEM-E7-12ME221-C1-310.5☐☐☐☐☐☐☐
W24OEM-E7-13ME221-C1-20.5☐☐☐☐☐☐☐
W25OEM-E6-5ME221-C1-630.5☐☐☐☐☐☐☐
W26OEM-E6-6ME221-C1-40.5☐☐☐☐☐☐☐
W27OEM-E7-1ME221-C1-330.5☐☐☐☐☐☐☐
W28OEM-E7-2ME221-C1-30.5☐☐☐☐☐☐☐
W29OEM-E7-3ME221-C1-630.5☐☐☐☐☐☐☐
W30OEM-E7-4ME221-C1-40.5☐☐☐☐☐☐☐
W31OEM-E7-17ME221-C1-730.5☐☐☐☐☐☐☐
W32OEM-E7-18ME221-C1-120.5☐☐☐☐☐☐☐
W33OEM-E7-19ME221-C1-740.5☐☐☐☐☐☐☐
W34OEM-E7-20ME221-C1-440.5☐☐☐☐☐☐☐
W35OEM-E6-15ME221-C1-260.5☐☐☐☐☐☐☐
W36OEM-E6-23ME221-C1-560.5☐☐☐☐☐☐☐
W37OEM-E6-16ME221-C1-170.5☐☐☐☐☐☐☐
W38OEM-E6-24ME221-C1-180.5☐☐☐☐☐☐☐
W39OEM-E6-14ME221-C1-860.5☐☐☐☐☐☐☐
W40OEM-E3-10ME221-C1-690.5☐☐☐☐☐☐☐
W41OEM-E3-4ME221-C1-390.5☐☐☐☐☐☐☐
W42OEM-E4-13ME221-C1-160.5☐☐☐☐☐☐☐
W43OEM-E2-25ME221-C1-370.5☐☐☐☐☐☐☐
W44OEM-E2-26ME221-C1-420.5☐☐☐☐☐☐☐
W45OEM-E6-3ME221-C1-720.5☐☐☐☐☐☐☐
W46OEM-E6-4ME221-C1-430.5☐☐☐☐☐☐☐
W47OEM-E6-22ME221-C1-570.5☐☐☐☐☐☐☐
W48OEM-E5-11ME221-C1-60.5☐☐☐☐☐☐☐
W49OEM-E5-5ME221-C1-70.5☐☐☐☐☐☐☐

Bench test (before first power-up)

Battery disconnected, ECU and every sensor unplugged. Meter on resistance. Each pair below must read open (OL): a reading means a pinched wire, a stray strand or a mis-pinned cavity. Then check continuity of every wire (last column of the build checklist).

#Probe AProbe BExpectWhyReading
1ME221-C1-15ME221-C1-10open (OL)+12 V supply must not touch power ground
2ME221-C1-15ME221-C1-52open (OL)+12 V supply must not touch sensor ground
3ME221-C1-10ME221-C1-45open (OL)power ground must not touch 5 V sensor reference
4ME221-C1-15ME221-C1-45open (OL)+12 V supply must not touch 5 V sensor reference
5ME221-C1-52ME221-C1-45open (OL)sensor ground must not touch 5 V sensor reference

If any reading doesn't match, stop and get help before powering up.

Revisions

RevLabelByDate
No revisions yet.

Schematic

ME221-C1OEM-E2OEM-E3OEM-E4OEM-E5OEM-E6OEM-E7SP-0VSP-14VSP-GND

Connectors

ME221-C1

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1COIL 4————————
10GROUND CHASSIS—W9—0.85SP-GND-1———
12LOW SIDE 2—W32—0.5OEM-E7-18———
14LSU +12V————————
15IGN +12V—W5—0.85SP-14V-1———
16LSU HEATER -VE—W42—0.5OEM-E4-13———
17ANA VOLT 3—W37—0.5OEM-E6-16———
18ANA VOLT 4—W38—0.5OEM-E6-24———
19LSU UN————————
2COIL 3—W24—0.5OEM-E7-13———
20LSU VM————————
21CAN 1 HIGH————————
22CAM A VR+—W20—0.5OEM-E7-10———
23CAM A VR-————————
24SERIAL 1 GROUND————————
25SERIAL 1 TX————————
26ANA VOLT 1—W35—0.5OEM-E6-15———
3INJECTOR 4—W28—0.5OEM-E7-2———
31COIL 2—W23—0.5OEM-E7-12———
32COIL 1—W22—0.5OEM-E7-11———
33INJECTOR 3—W27—0.5OEM-E7-1———
35USB D+————————
36USB D-————————
37LOW SIDE RELAY 11—W43—0.5OEM-E2-25———
38USB VBUS————————
39LOW SIDE 6—W41—0.5OEM-E3-4———
4INJECTOR 2—W26—0.5OEM-E6-6———
4INJECTOR 2—W30—0.5OEM-E7-4———
41USB GROUND————————
42LOW SIDE RELAY 12—W44—0.5OEM-E2-26———
43LOW SIDE RELAY 14—W46—0.5OEM-E6-4———
44LOW SIDE 4—W34—0.5OEM-E7-20———
455V REF—W18—0.5OEM-E6-2———
465V REF————————
49LSU IA————————
50LSU IP————————
51CAN 1 LOW————————
52SENSORS GROUND—W16—0.5SP-0V-1———
53KNOCK 1 SIGNAL—W21—0.5OEM-E7-28———
55SERIAL 1 RX————————
56ANA VOLT 2—W36—0.5OEM-E6-23———
57ANA TEMP 2—W47—0.5OEM-E6-22———
6DIG_IN 1—W48—0.5OEM-E5-11———
61GROUND—W10—0.85SP-GND-1———
63INJECTOR 1—W25—0.5OEM-E6-5———
63INJECTOR 1—W29—0.5OEM-E7-3———
64VBAT—W6—0.85SP-14V-1———
67Stepper 1 / A1————————
68Stepper 2 / A2————————
69LOW SIDE 5—W40—0.5OEM-E3-10———
7DIG_IN 2—W49—0.5OEM-E5-5———
70Stepper 3 / B1————————
71Stepper 4 / B2————————
72LOW SIDE RELAY 13—W45—0.5OEM-E6-3———
73LOW SIDE 1—W31—0.5OEM-E7-17———
74LOW SIDE 3—W33—0.5OEM-E7-19———
765V REF————————
79TACHOMETER————————
80CRANK VR+—W19—0.5OEM-E7-23———
81CRANK VR-————————
84Sensor Ground—W17—0.5SP-0V-1———
86ANA TEMP 1—W39—0.5OEM-E6-14———
89GROUND—W11—0.85SP-GND-1———
90GROUND—W12—0.85SP-GND-1———

OEM-E2

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
13ETCS power (TBP, throttle bypass)—W1—0.85SP-14V-1———
24O2 right rear (OXR2)————————
25O2 heater right rear (HTR2)—W43—0.5ME221-C1-37———
26O2 heater left rear (HTL2)—W44—0.5ME221-C1-42———

OEM-E3

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1Battery constant (BATT)————————
10EFI main relay control (MREL)—W40—0.5ME221-C1-69———
11Serial diagnostic (SIL)————————
16EFI main relay (+B)—W2—0.85SP-14V-1———
4Fuel pump relay (FPR)—W41—0.5ME221-C1-39———
5Fuel pump control (FC)————————
6Check-engine lamp (W)————————
7ETCS main relay (+BM)—W3—0.85SP-14V-1———
8EFI main relay (+B2)—W4—0.85SP-14V-1———
9Ignition switch (IGSW)————————

OEM-E4

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
13A/C clutch relay (ACMG)—W42—0.5ME221-C1-16———
18EVAP vapor pressure (PTNK)————————
2Starter signal (STA)————————
5Diagnostic/timing check (TC)————————
6Stop light switch (STP)————————
8O2 left rear (OXL2)————————

OEM-E5

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
11Vehicle speed sensor (SP2-)—W48—0.5ME221-C1-6———
12Canister close valve (CCV)————————
5Vehicle speed sensor (SP2+)—W49—0.5ME221-C1-7———

OEM-E6

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
10Mass air flow (VG)————————
11O2 right front (OXR1)————————
12O2 left front (OXL1)————————
14Coolant temperature (THW)—W39—0.5ME221-C1-86———
15Accelerator pedal 1 (VPA)—W35—0.5ME221-C1-26———
16Accelerator pedal 2 (VPA2)—W37—0.5ME221-C1-17———
17Power ground (E1)—W7—0.85SP-GND-1———
18Sensor ground (E2)—W13—0.5SP-0V-1———
19MAF ground (EVG)—W14—0.5SP-0V-1———
2Sensor supply +5V (VC)—W18—0.5ME221-C1-45———
22Intake air temperature (THA)—W47—0.5ME221-C1-57———
23Throttle position 1 (VTA)—W36—0.5ME221-C1-56———
24Throttle position 2 (VTA2)—W38—0.5ME221-C1-18———
3O2 heater right front (HTR)—W45—0.5ME221-C1-72———
4O2 heater left front (HTL)—W46—0.5ME221-C1-43———
5Injector 1 (#10)—W25—0.5ME221-C1-63———
6Injector 2 (#20)—W26—0.5ME221-C1-4———
7EVAP purge VSV (PRG)————————

OEM-E7

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1Injector 3 (#30)—W27—0.5ME221-C1-33———
10Cam position (G2)—W20—0.5ME221-C1-22———
11Ignition 1 (IGT)—W22—0.5ME221-C1-32———
12Ignition 2 (IGT2)—W23—0.5ME221-C1-31———
13Ignition 3 (IGT3)—W24—0.5ME221-C1-2———
17VVT-i OCV - (OCV-)—W31—0.5ME221-C1-73———
18VVT-i OCV + (OCV+)—W32—0.5ME221-C1-12———
19ETCS throttle clutch - (CL-)—W33—0.5ME221-C1-74———
2Injector 4 (#40)—W28—0.5ME221-C1-3———
20ETCS throttle clutch + (CL+)—W34—0.5ME221-C1-44———
21Power ground (E01)—W8—0.85SP-GND-1———
22Crank position return (NE-)—W15—0.5SP-0V-1———
23Crank position (NE)—W19—0.5ME221-C1-80———
25Igniter feedback (IGF)————————
27Knock sensor 2 (KNK2)————————
28Knock sensor 1 (KNK1)—W21—0.5ME221-C1-53———
3Injector 5 (#50)—W29—0.5ME221-C1-63———
4Injector 6 (#60)—W30—0.5ME221-C1-4———
5ACIS intake VSV————————
7ETCS throttle motor - (M-)————————
8ETCS throttle motor + (M+)————————

SP-0V

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1——W13—0.5OEM-E6-18———
1——W14—0.5OEM-E6-19———
1——W15—0.5OEM-E7-22———
1——W16—0.5ME221-C1-52———
1——W17—0.5ME221-C1-84———

SP-14V

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1——W1—0.85OEM-E2-13———
1——W2—0.85OEM-E3-16———
1——W3—0.85OEM-E3-7———
1——W4—0.85OEM-E3-8———
1——W5—0.85ME221-C1-15———
1——W6—0.85ME221-C1-64———

SP-GND

CavityFunctionSignalWireColourGauge (mm²)DestinationTerminalSealPlug
1——W7—0.85OEM-E6-17———
1——W8—0.85OEM-E7-21———
1——W9—0.85ME221-C1-10———
1——W10—0.85ME221-C1-61———
1——W11—0.85ME221-C1-89———
1——W12—0.85ME221-C1-90———

Pin map

OEM pointOEM functionOEM familyTarget pointTarget functionTarget familyWire colourEvidence
OEM-E2-13ETCS power (TBP, throttle bypass)power_inME221-C1-15 + ME221-C1-64IGN +12V + VBATpower_insingle_source
OEM-E2-24O2 right rear (OXR2)lambda_nb_in———single_source
OEM-E2-25O2 heater right rear (HTR2)low_side_outME221-C1-37LOW SIDE RELAY 11low_side_outsingle_source
OEM-E2-26O2 heater left rear (HTL2)low_side_outME221-C1-42LOW SIDE RELAY 12low_side_outsingle_source
OEM-E3-1Battery constant (BATT)power_in———single_source
OEM-E3-10EFI main relay control (MREL)low_side_outME221-C1-69LOW SIDE 5low_side_outsingle_source
OEM-E3-11Serial diagnostic (SIL)serial———single_source
OEM-E3-16EFI main relay (+B)power_inME221-C1-15 + ME221-C1-64IGN +12V + VBATpower_insingle_source
OEM-E3-4Fuel pump relay (FPR)low_side_outME221-C1-39LOW SIDE 6low_side_outsingle_source
OEM-E3-5Fuel pump control (FC)low_side_out———single_source
OEM-E3-6Check-engine lamp (W)low_side_out———single_source
OEM-E3-7ETCS main relay (+BM)power_inME221-C1-15 + ME221-C1-64IGN +12V + VBATpower_insingle_source
OEM-E3-8EFI main relay (+B2)power_inME221-C1-15 + ME221-C1-64IGN +12V + VBATpower_insingle_source
OEM-E3-9Ignition switch (IGSW)digital_in———single_source
OEM-E4-13A/C clutch relay (ACMG)low_side_outME221-C1-16LSU HEATER -VElow_side_outsingle_source
OEM-E4-18EVAP vapor pressure (PTNK)analog_in———single_source
OEM-E4-2Starter signal (STA)digital_in———single_source
OEM-E4-5Diagnostic/timing check (TC)digital_in———single_source
OEM-E4-6Stop light switch (STP)digital_in———single_source
OEM-E4-8O2 left rear (OXL2)lambda_nb_in———single_source
OEM-E5-11Vehicle speed sensor (SP2-)digital_inME221-C1-6DIG_IN 1digital_insingle_source
OEM-E5-12Canister close valve (CCV)low_side_out———single_source
OEM-E5-5Vehicle speed sensor (SP2+)digital_inME221-C1-7DIG_IN 2digital_insingle_source
OEM-E6-10Mass air flow (VG)analog_in———single_source
OEM-E6-11O2 right front (OXR1)lambda_nb_in———single_source
OEM-E6-12O2 left front (OXL1)lambda_nb_in———single_source
OEM-E6-14Coolant temperature (THW)temp_inME221-C1-86ANA TEMP 1temp_insingle_source
OEM-E6-15Accelerator pedal 1 (VPA)analog_inME221-C1-26ANA VOLT 1analog_insingle_source
OEM-E6-16Accelerator pedal 2 (VPA2)analog_inME221-C1-17ANA VOLT 3analog_insingle_source
OEM-E6-17Power ground (E1)groundME221-C1-10 + ME221-C1-61 + ME221-C1-89 + ME221-C1-90GROUND CHASSIS + GROUND + GROUND + GROUNDgroundsingle_source
OEM-E6-18Sensor ground (E2)sensor_groundME221-C1-52 + ME221-C1-84SENSORS GROUND + Sensor Groundsensor_groundsingle_source
OEM-E6-19MAF ground (EVG)sensor_groundME221-C1-52 + ME221-C1-84SENSORS GROUND + Sensor Groundsensor_groundsingle_source
OEM-E6-2Sensor supply +5V (VC)vrefME221-C1-455V REFvrefsingle_source
OEM-E6-22Intake air temperature (THA)temp_inME221-C1-57ANA TEMP 2temp_insingle_source
OEM-E6-23Throttle position 1 (VTA)analog_inME221-C1-56ANA VOLT 2analog_insingle_source
OEM-E6-24Throttle position 2 (VTA2)analog_inME221-C1-18ANA VOLT 4analog_insingle_source
OEM-E6-3O2 heater right front (HTR)low_side_outME221-C1-72LOW SIDE RELAY 13low_side_outsingle_source
OEM-E6-4O2 heater left front (HTL)low_side_outME221-C1-43LOW SIDE RELAY 14low_side_outsingle_source
OEM-E6-5Injector 1 (#10)injector_outME221-C1-63INJECTOR 1injector_outsingle_source
OEM-E6-6Injector 2 (#20)injector_outME221-C1-4INJECTOR 2injector_outsingle_source
OEM-E6-7EVAP purge VSV (PRG)low_side_out———single_source
OEM-E7-1Injector 3 (#30)injector_outME221-C1-33INJECTOR 3injector_outsingle_source
OEM-E7-10Cam position (G2)trigger_inME221-C1-22CAM A VR+trigger_insingle_source
OEM-E7-11Ignition 1 (IGT)ignition_outME221-C1-32COIL 1ignition_outsingle_source
OEM-E7-12Ignition 2 (IGT2)ignition_outME221-C1-31COIL 2ignition_outsingle_source
OEM-E7-13Ignition 3 (IGT3)ignition_outME221-C1-2COIL 3ignition_outsingle_source
OEM-E7-17VVT-i OCV - (OCV-)low_side_outME221-C1-73LOW SIDE 1low_side_outsingle_source
OEM-E7-18VVT-i OCV + (OCV+)low_side_outME221-C1-12LOW SIDE 2low_side_outsingle_source
OEM-E7-19ETCS throttle clutch - (CL-)low_side_outME221-C1-74LOW SIDE 3low_side_outsingle_source
OEM-E7-2Injector 4 (#40)injector_outME221-C1-3INJECTOR 4injector_outsingle_source
OEM-E7-20ETCS throttle clutch + (CL+)low_side_outME221-C1-44LOW SIDE 4low_side_outsingle_source
OEM-E7-21Power ground (E01)groundME221-C1-10 + ME221-C1-61 + ME221-C1-89 + ME221-C1-90GROUND CHASSIS + GROUND + GROUND + GROUNDgroundsingle_source
OEM-E7-22Crank position return (NE-)sensor_groundME221-C1-52 + ME221-C1-84SENSORS GROUND + Sensor Groundsensor_groundsingle_source
OEM-E7-23Crank position (NE)trigger_inME221-C1-80CRANK VR+trigger_insingle_source
OEM-E7-25Igniter feedback (IGF)digital_in———single_source
OEM-E7-27Knock sensor 2 (KNK2)knock_in———single_source
OEM-E7-28Knock sensor 1 (KNK1)knock_inME221-C1-53KNOCK 1 SIGNALknock_insingle_source
OEM-E7-3Injector 5 (#50)injector_outME221-C1-63INJECTOR 1injector_outsingle_source
OEM-E7-4Injector 6 (#60)injector_outME221-C1-4INJECTOR 2injector_outsingle_source
OEM-E7-5ACIS intake VSVlow_side_out———single_source
OEM-E7-7ETCS throttle motor - (M-)hbridge_out———single_source
OEM-E7-8ETCS throttle motor + (M+)hbridge_out———single_source

Cut list

WireFromToGauge (mm²)ColourLengthSignalIdent
W1OEM-E2-13SP-14V-10.85no routeETCS power (TBP, throttle bypass)—
W2OEM-E3-16SP-14V-10.85no routeEFI main relay (+B)—
W3OEM-E3-7SP-14V-10.85no routeETCS main relay (+BM)—
W4OEM-E3-8SP-14V-10.85no routeEFI main relay (+B2)—
W5SP-14V-1ME221-C1-150.85no routeIGN +12V—
W6SP-14V-1ME221-C1-640.85no routeVBAT—
W7OEM-E6-17SP-GND-10.85no routePower ground (E1)—
W8OEM-E7-21SP-GND-10.85no routePower ground (E01)—
W9SP-GND-1ME221-C1-100.85no routeGROUND CHASSIS—
W10SP-GND-1ME221-C1-610.85no routeGROUND—
W11SP-GND-1ME221-C1-890.85no routeGROUND—
W12SP-GND-1ME221-C1-900.85no routeGROUND—
W13OEM-E6-18SP-0V-10.5no routeSensor ground (E2)—
W14OEM-E6-19SP-0V-10.5no routeMAF ground (EVG)—
W15OEM-E7-22SP-0V-10.5no routeCrank position return (NE-)—
W16SP-0V-1ME221-C1-520.5no routeSENSORS GROUND—
W17SP-0V-1ME221-C1-840.5no routeSensor Ground—
W18OEM-E6-2ME221-C1-450.5no routeSensor supply +5V (VC)—
W19OEM-E7-23ME221-C1-800.5no routeCrank position (NE)—
W20OEM-E7-10ME221-C1-220.5no routeCam position (G2)—
W21OEM-E7-28ME221-C1-530.5no routeKnock sensor 1 (KNK1)—
W22OEM-E7-11ME221-C1-320.5no routeIgnition 1 (IGT)—
W23OEM-E7-12ME221-C1-310.5no routeIgnition 2 (IGT2)—
W24OEM-E7-13ME221-C1-20.5no routeIgnition 3 (IGT3)—
W25OEM-E6-5ME221-C1-630.5no routeInjector 1 (#10)—
W26OEM-E6-6ME221-C1-40.5no routeInjector 2 (#20)—
W27OEM-E7-1ME221-C1-330.5no routeInjector 3 (#30)—
W28OEM-E7-2ME221-C1-30.5no routeInjector 4 (#40)—
W29OEM-E7-3ME221-C1-630.5no routeInjector 5 (#50)—
W30OEM-E7-4ME221-C1-40.5no routeInjector 6 (#60)—
W31OEM-E7-17ME221-C1-730.5no routeVVT-i OCV - (OCV-)—
W32OEM-E7-18ME221-C1-120.5no routeVVT-i OCV + (OCV+)—
W33OEM-E7-19ME221-C1-740.5no routeETCS throttle clutch - (CL-)—
W34OEM-E7-20ME221-C1-440.5no routeETCS throttle clutch + (CL+)—
W35OEM-E6-15ME221-C1-260.5no routeAccelerator pedal 1 (VPA)—
W36OEM-E6-23ME221-C1-560.5no routeThrottle position 1 (VTA)—
W37OEM-E6-16ME221-C1-170.5no routeAccelerator pedal 2 (VPA2)—
W38OEM-E6-24ME221-C1-180.5no routeThrottle position 2 (VTA2)—
W39OEM-E6-14ME221-C1-860.5no routeCoolant temperature (THW)—
W40OEM-E3-10ME221-C1-690.5no routeEFI main relay control (MREL)—
W41OEM-E3-4ME221-C1-390.5no routeFuel pump relay (FPR)—
W42OEM-E4-13ME221-C1-160.5no routeA/C clutch relay (ACMG)—
W43OEM-E2-25ME221-C1-370.5no routeO2 heater right rear (HTR2)—
W44OEM-E2-26ME221-C1-420.5no routeO2 heater left rear (HTL2)—
W45OEM-E6-3ME221-C1-720.5no routeO2 heater right front (HTR)—
W46OEM-E6-4ME221-C1-430.5no routeO2 heater left front (HTL)—
W47OEM-E6-22ME221-C1-570.5no routeIntake air temperature (THA)—
W48OEM-E5-11ME221-C1-60.5no routeVehicle speed sensor (SP2-)—
W49OEM-E5-5ME221-C1-70.5no routeVehicle speed sensor (SP2+)—

Bill of materials

CategoryPart numberManufacturerDescriptionQtyUnit

ECU setup sheet

RoleEngine refEngine signalSensorECU pointECU functionECU classSetup flag
No configured channels.

Findings

Open (7)

SeverityCodeSubjectMessage
errorNET_MERGEDME221-C1-4 + OEM-E6-6 + OEM-E7-42 different OEM functions share one net: OEM-E6-6 Injector 2 (#20); OEM-E7-4 Injector 6 (#60)
errorNET_MERGEDME221-C1-63 + OEM-E6-5 + OEM-E7-32 different OEM functions share one net: OEM-E6-5 Injector 1 (#10); OEM-E7-3 Injector 5 (#50)
errorREQUIRED_UNMAPPEDOEM-E3-9Required OEM function "Ignition switch (IGSW)" (digital_in) is not connected to the new ECU.
errorREQUIRED_UNMAPPEDOEM-E7-7Required OEM function "ETCS throttle motor - (M-)" (hbridge_out) is not connected to the new ECU.
errorREQUIRED_UNMAPPEDOEM-E7-8Required OEM function "ETCS throttle motor + (M+)" (hbridge_out) is not connected to the new ECU.
warnLOAD_UNKNOWNME221-C1-16ME221-C1-16 "LSU HEATER -VE" drives OEM-E4-13 A/C clutch relay (ACMG) (load 0.2 A) but its current rating is unknown. Check the ECU manual.
infoUNMAPPEDOEM17 optional OEM pins are not mapped: OEM-E2-24 O2 right rear (OXR2); OEM-E3-11 Serial diagnostic (SIL); OEM-E3-5 Fuel pump control (FC); OEM-E3-6 Check-engine lamp (W); OEM-E4-18 EVAP vapor pressure (PTNK); OEM-E4-2 Starter signal (STA); OEM-E4-5 Diagnostic/timing check (TC); OEM-E4-6 Stop light switch (STP); OEM-E4-8 O2 left rear (OXL2); OEM-E5-12 Canister close valve (CCV); OEM-E6-10 Mass air flow (VG); OEM-E6-11 O2 right front (OXR1); OEM-E6-12 O2 left front (OXL1); OEM-E6-7 EVAP purge VSV (PRG); OEM-E7-25 Igniter feedback (IGF); OEM-E7-27 Knock sensor 2 (KNK2); OEM-E7-5 ACIS intake VSV

Accepted (1)

CodeSubjectReasonBy
REQUIRED_UNMAPPEDOEM-E3-1Battery-constant (memory) feed of the stock ECU: the new ECU has no such input, so it is not needed.mapping-proposal

Notes

Fit check: needs add-on. Resolve these before building: - No drive-by-wire; needs a cable-throttle conversion or an external DBW controller - Trigger pattern for Toyota 2JZ not found in the ECU's docs (Trigger-pattern list is only inside MEITE software, not published online) - Only 4 ignition outputs for 6 cylinders: wasted spark (pair coils per firing order) - Only 4 injector outputs for 6 injectors: batch / semi-sequential injection Auto-mapped by auto_map() from the library pin data on 2026-10-11. Review every wire against both manuals before building. Open items: - OEM-E3 9: Ignition switch (IGSW): key-on 12 V sense — optional in a swap (the main relay is energized from keyed 12 V, not from this pin); Motorsport Electronics ME221 has no dedicated key-on input - OEM-E7 7: ETCS throttle motor - (M-): no +/− pair in the pinout (multi-phase or half-documented motor); wire by hand - OEM-E7 8: ETCS throttle motor + (M+): no +/− pair in the pinout (multi-phase or half-documented motor); wire by hand Not wired: - OEM-E3 1: Battery constant (BATT): Motorsport Electronics ME221 has no battery-constant input; not needed - OEM-E7 27: Knock sensor 2 (KNK2): no free knock input on Motorsport Electronics ME221 - OEM-E3 5: Fuel pump control (FC): no free low_side/relay_control/heater_low_side/ls_hs/injector on Motorsport Electronics ME221 - OEM-E3 6: Check-engine lamp (W): no free low_side/relay_control/heater_low_side/ls_hs/injector on Motorsport Electronics ME221 - OEM-E5 12: Canister close valve (CCV): no free low_side/relay_control/heater_low_side/ls_hs/injector on Motorsport Electronics ME221 - OEM-E6 7: EVAP purge VSV (PRG): no free low_side/relay_control/heater_low_side/ls_hs/injector on Motorsport Electronics ME221 - OEM-E7 5: ACIS intake VSV: no free low_side/relay_control/heater_low_side/ls_hs/injector on Motorsport Electronics ME221 - OEM-E6 10: Mass air flow (VG): no free maf/analog_0_5 on Motorsport Electronics ME221 - OEM-E2 24: O2 right rear (OXR2): no free o2_narrowband/analog_0_5 on Motorsport Electronics ME221 - OEM-E4 8: O2 left rear (OXL2): no free o2_narrowband/analog_0_5 on Motorsport Electronics ME221 - OEM-E6 11: O2 right front (OXR1): no free o2_narrowband/analog_0_5 on Motorsport Electronics ME221 - OEM-E6 12: O2 left front (OXL1): no free o2_narrowband/analog_0_5 on Motorsport Electronics ME221 - OEM-E4 18: EVAP vapor pressure (PTNK): no free analog_0_5 on Motorsport Electronics ME221 - OEM-E7 25: Igniter feedback (IGF): no free frequency_in/switch_in on Motorsport Electronics ME221 - OEM-E4 2: Starter signal (STA): no free switch_in/frequency_in/analog_0_5 on Motorsport Electronics ME221 - OEM-E4 5: Diagnostic/timing check (TC): no free switch_in/frequency_in/analog_0_5 on Motorsport Electronics ME221 - OEM-E4 6: Stop light switch (STP): no free switch_in/frequency_in/analog_0_5 on Motorsport Electronics ME221 - OEM-E3 11: Serial diagnostic (SIL): no free k_line on Motorsport Electronics ME221

Sources

ReliabilityKindTitleURLArchiveCapturedSHA-256
4vendor_docMotorsport Electronics GEN2 ME221/ME360/ME442 wire-in pinouthttps://motorsport-electronics.co.uk/onlinehelp/html/ME442ME360ME221GEN2Wire-InPinout.html———
4service_manualToyota FSM RM779U (2001 Lexus IS300) — DIAGNOSTICS 'TERMINALS OF ECM' (DI-20/21)http://www.2jzgarage.com/wp-content/uploads/2013/04/2001_IS300_ECU_Pinouts.pdf———